SERVICE OFFERINGS

Spatial and Single Cell Applications

Compare capabilities to find the right solution for your research

Whole-transcriptome VisiumHD Spatial services

Visium HD assays

Single-cell–scale resolution

Probe-based chemistry
Supports human & mouse FFPE, fresh-frozen, and fixed-frozen tissue 

Reverse-transcription–based chemistry
Species-agnostic fresh-frozen tissue compatibility

Multiomic readouts from the same section:
Gene expression
Protein co-detection (immunofluorescence)
Morphology (H&E)

Featured Single-cell assays from 10x Genomics.

Blue wave pattern
Chromium Single Cell

GEM-X Flex Gene Expression

Comprehensive whole-transcriptome gene expression with unmatched flexibility in sample prep and the freedom to fix, batch, and process samples on your own schedule.

Recommended for experiments that…

  • Use archival or lower-quality samples
  • Require flexible sample batching
  • Will scale up and require the lowest cost per-cell
Blue wave pattern
Chromium Single Cell

GEM-X Universal 3’ Gene Expression

This is a flexible 3′ gene expression platform with built-in multiomic analysis capabilities.

Recommended for experiments that…

  • Require full-length transcript readouts, with or without simultaneous protein expression
  • Only require gene expression, or may use ATAC in the future
  • Have lower cell input requirements
Blue wave pattern
Chromium Single Cell

GEM-X Universal 5’ Gene Expression

In‐depth immune diversity analysis uniting 5′ gene expression with advanced multiomic workflows.

Recommended for experiments that…

  • Require full length transcript readouts, with or without simultaneous protein expression
  • Require or may use CRISPR and TCR/BCR sequencing in the future
  • Have lower cell input requirements

Additional CRO Services

Confocal Portrait

High Resolution Imaging

  • Biomarker imaging for spatial multiomics
  • Proteomic vaildation of spatially distinct cell states
A diagram illustrating flow cytometry, showing different cell types (cytotoxic T-lymphocytes, T helper lymphocytes, other leukocytes) with specific surface markers (CD3, CD4, CD8) passing through a flow cell where they are illuminated by a laser and detected by a sensor. The resulting fluorescence data is presented as a 2-dimensional dot plot and 1-dimensional histograms, identifying 60% CD4-positive cells and 25% CD8-positive cells.

FACS isolation of Cell Subsets

  • Bulk cell enrichment by magnetic bead isolation
  • Antibody specific cell type isolation by FACS
JavaScript code being displayed on a monitor

In-Depth Bioinformatics

  • Detailed informatics and data visualization
  • Data integration for multiomics
  • Custom analysis workflows
Four fluorescent microscopy images comparing 'Cleared' (cyan, left) and 'Expanded' (magenta, right) cellular spheroids, with 'Endogenous' (top) and 'Immuno-stain' (bottom) fluorescent signals. Expanded spheroids are dramatically larger and reveal finely resolved internal cellular structures compared to the more compact cleared samples. White dashed lines indicate the approximate center of each spheroid.

High Content Imaging

  • High Content Analysis/Screening
  • 2D, co-culture, 3D imaging
  • Drug response HCS
  • Cell Painting assay
A diagram illustrating the transfer of 'required volumes' from four individual 96-well compound plates (green, blue, red, orange) into a single 384-well destination plate. Each 96-well plate fills one distinct quadrant of the 384-well plate. An inset shows how the A1 wells from each of the four 96-well plates contribute to specific sub-wells within the A1 area of the 384-well plate.

Custom Assay Development

  • Compound validation assays
  • Complex dosing schemes
  • Full gamut of phenotypic and molecular readouts

Ready to move your spatial and single cell research forward?

Whether you’re planning a new study or building on prior work, we can help you achieve your research goals.

Privacy Overview
3D Genomics Logo

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.

Strictly Necessary Cookies

Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings.

Analytics

This website uses Google Analytics to collect anonymous information such as the number of visitors to the site, and the most popular pages.

Keeping this cookie enabled helps us to improve our website.